CEPCD surveillance shows more than 4,000 cases of Candidozyma auris reported across the EU from 2013–2023, with an apparent surge recorded in 2025. In Portugal the pathogen was first confirmed in eight patients at a northern hospital in 2023. The pattern underscores nurses’ frontline role in detection, infection control and patient care, and highlights gaps in surveillance, preparedness and resource allocation that must be addressed to limit spread and protect vulnerable patients and healthcare staff.